Even the most well-designed protocols can encounter unexpected challenges once a trial is underway. Procedures that seem straightforward on paper may prove burdensome in practice. Eligibility criteria that appear reasonable may limit enrollment more than anticipated. Small[...]

Clinical trial success hinges on a strong foundation, and that foundation is protocol design. It’s the blueprint that guides everything from study startup and patient enrollment to data collection and final analysis. But what happens when that blueprint for conducting the trial[...]